What are the functions of luminescent reagent acridine ester ME-DMAE-NHS?

Acridine ester ME-DMAE-NHS is an important chemiluminescence reagent with unique chemical structure and superior performance, which can be used for labeling and detection of biomolecules such as proteins, antibodies, and nucleic acids. Therefore, it has been widely used in biomedical and molecular biology research. Below, we will provide a detailed introduction to its role in various fields.

Acridine ester ME-DMAE-NHS is a luminescent reagent with a long chain structure, mainly composed of functional groups such as maleimide mercaptoethyl and dimethylaminoethyl. This special structure gives it strong affinity on biomolecules, allowing it to react with amino and thiol groups in proteins and nucleic acids through nucleophilic reactions, achieving effective labeling. Its functions are roughly as follows:

1. Acridine ester ME-DMAE-NHS is commonly used for labeling proteins and antibodies in biomedical research. It can react with amino groups (Lysine) in proteins and thiol groups (Cysteine) in antibodies to form stable amide or thioether bonds, introducing chemiluminescent markers into target proteins or antibodies. This type of marker can play an important role in fields such as biological analysis, immune testing, and drug development.

2. Immunoassay is an important biological analysis technique widely used for early diagnosis of diseases and drug development. Acridine ester ME-DMAE-NHS can be used to introduce fluorescent labeling into antibodies, enabling them to bind to specific antigens and generate fluorescent signals, thereby achieving rapid and highly sensitive immune detection.

3. In the field of protein research, acridine ester ME-DMAE-NHS is also widely used to introduce chemiluminescence labeling into proteins for studying their structure, function, and interactions. Fluorescent labeled proteins can be tracked in real-time within living organisms, allowing for a better understanding of their biological functions.

4. With the continuous development of biomedical research, it has been found that acridine ester ME-DMAE-NHS also has great potential for application in drug analysis. For example, it can undergo chemical reactions with drug molecules, introducing chemiluminescent markers into drug molecules to achieve fluorescence tracing and monitoring of drugs, providing new methods for drug development and efficacy evaluation.

Acridine ester ME-DMAE-NHS, as an important chemiluminescence reagent, has broad application prospects in the biomedical field. It achieves efficient labeling of biomolecules by reacting with amino and thiol groups in proteins and antibodies. As a leading producer of acridine esters, Desheng can provide customers with six different groups of acridine esters to meet diverse needs and save time and costs. At the same time, due to direct sales from the manufacturer, the price can be flexibly adjusted according to the order quantity. If you have any needs, please feel free to contact us!